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Les hormones T3 et T4 vont circuler dans le sang liées à une protéine la TBG (thyroxin Binding Globulin). Une petite partie de ces hormones ( T3L et T4L ) va circuler libre dans le sang sans liaison à la TBG; ce sont les seules fractions physiologiquement actives et ce sont les seules fractions actuellement dosées dans les laboratoires de biol